SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03761

Signal sequence   MAPLKMLALVTLLLGASLQHIHA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  Q92583,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03761.cif

Structure  SPKB03761.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2442.06234

Aliphatic index  165.6521739

Isoelectric point  9.703982825

Charge (pH=7)   1.179507447

Topological polar surface area  861.66

Aromaticity  0

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  32

X logP energy  -3.4887

Hydropathy 



Literature Information


Title  Molecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector.

DOI  10.1074/jbc.271.35.21514,

Publication Year  1996

PubMed ID  8702936,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.