SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03759

Signal sequence   MGACRIQYILLVFLLIASHWTLVQN

Length  25

Organism  Rattus norvegicus (Rat)

UniProt ID  Q924B5,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03759.cif

Structure  SPKB03759.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2903.53944

Aliphatic index  156

Isoelectric point  8.534796248

Charge (pH=7)   1.026064949

Topological polar surface area  1058.05

Aromaticity  0.12

Average rotatable bonds  3.72

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  36

X logP energy  -4.00803

Hydropathy 



Literature Information


Title  A novel lipid raft-associated glycoprotein, TEC-21, activates rat basophilic leukemia cells independently of the type 1 Fc epsilon receptor.

DOI  10.1093/intimm/14.2.213,

Publication Year  2002

PubMed ID  11809740,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.