SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03757

Signal sequence   METALTKTPEKRQVIFLAILLLLWEASS

Length  28

Organism  Mus musculus (Mouse)

UniProt ID  Q91XZ2,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03757.cif

Structure  SPKB03757.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3202.84314

Aliphatic index  132.5

Isoelectric point  6.609123132

Charge (pH=7)   0.002716289

Topological polar surface area  1226.1

Aromaticity  0.071428571

Average rotatable bonds  3.821428571

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  42

X logP energy  -6.69343

Hydropathy 



Literature Information


Title  Structural Basis of Diverse Homophilic Recognition by Clustered alpha-and beta-Protocadherins.

DOI  10.1016/j.neuron.2016.04.004,

Publication Year  2016

PubMed ID  27161523,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.