SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03756

Signal sequence   MAKLLLVTGLALLLNAQLGSA

Length  21

Organism  Mus musculus (Mouse)

UniProt ID  Q91XA9,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8FG5,

Predicted Structure ID  SPKB03756.cif

Structure  SPKB03756.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2110.62654

Aliphatic index  181.4285714

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  797.98

Aromaticity  0

Average rotatable bonds  3.428571429

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -5.1424

Hydropathy 



Literature Information


Title  Identification of a novel acidic mammalian chitinase distinct from chitotriosidase.

DOI  10.1074/jbc.M009886200,

Publication Year  2001

PubMed ID  11085997,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.