SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03753

Signal sequence   MYFLGLLSLLVLPSKA

Length  16

Organism  Gallus gallus (Chicken)

UniProt ID  Q90935,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03753.cif

Structure  SPKB03753.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1765.22734

Aliphatic index  170.625

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  577.74

Aromaticity  0.125

Average rotatable bonds  3.5

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  22

X logP energy  -0.1819

Hydropathy 



Literature Information


Title  Neuroserpin, an axonally secreted serine protease inhibitor.

DOI  NA,

Publication Year  1996

PubMed ID  8670795,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.