SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03752

Signal sequence   MKTHSVFGFFFKVLLIQVYLFNKTLA

Length  26

Organism  Gallus gallus (Chicken)

UniProt ID  Q90611,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03752.cif

Structure  SPKB03752.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3092.77864

Aliphatic index  112.3076923

Isoelectric point  10.64295713

Charge (pH=7)   3.087157875

Topological polar surface area  1064.66

Aromaticity  0.230769231

Average rotatable bonds  3.884615385

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  38

X logP energy  -2.4694

Hydropathy 



Literature Information


Title  Isolation and characterization of a 70-kDa metalloprotease (gelatinase) that is elevated in Rous sarcoma virus-transformed chicken embryo fibroblasts.

DOI  NA,

Publication Year  1991

PubMed ID  1848240,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.