SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03749

Signal sequence   MARYMLLLLLAVWVLTGELWPGAEA

Length  25

Organism  Homo sapiens (Human)

UniProt ID  Q8WXF3,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03749.cif

Structure  SPKB03749.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2817.44314

Aliphatic index  148.4

Isoelectric point  4.258146502

Charge (pH=7)   -0.999319181

Topological polar surface area  961.47

Aromaticity  0.12

Average rotatable bonds  3.48

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -0.20703

Hydropathy 



Literature Information


Title  Production of recombinant human relaxin 3 in AtT20 cells.

DOI  10.1016/s0167-0115(02)00304-x,

Publication Year  2003

PubMed ID  12686464,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.