General Information
SPKB ID SPKB03747
Signal sequence MGAAGRQDFLFKAMLTISWLTLTCFPGATS
Length 30
Organism Homo sapiens (Human)
UniProt ID Q8WUJ3,
Motif 1..30
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03747.cif
Physicochemical Information
Molecular weight 3235.82454
Aliphatic index 78.33333333
Isoelectric point 8.545113874
Charge (pH=7) 0.936157722
Topological polar surface area 1203.91
Aromaticity 0.133333333
Average rotatable bonds 3.4
Number of hydrogen bond donors 44
Number of hydrogen bond acceptors 44
X logP energy -10.30363
Hydropathy 
Literature Information
Title N-Terminal signal sequence is required for cellular trafficking and hyaluronan-depolymerization of KIAA1199.
DOI 10.1016/j.febslet.2013.11.017,
Publication Year 2014
PubMed ID 24269685,
Patent ID NA,
