SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03744

Signal sequence   MGCLCLYRSTLLTGGLLFLLMLADPAFPA

Length  29

Organism  Bos taurus (Bovine)

UniProt ID  Q8WMP9,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03744.cif

Structure  SPKB03744.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3101.83184

Aliphatic index  131.3793103

Isoelectric point  6.062626324

Charge (pH=7)   -0.126372374

Topological polar surface area  1040.66

Aromaticity  0.103448276

Average rotatable bonds  3.310344828

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  40

X logP energy  -4.35473

Hydropathy 



Literature Information


Title  Cloning and characterization of a lysosomal phospholipase A2, 1-O-acylceramide synthase.

DOI  10.1074/jbc.M111977200,

Publication Year  2002

PubMed ID  11790796,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.