SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03743

Signal sequence   MTPDIQAPFLSLLLLFPVLTVA

Length  22

Organism  Bos taurus (Bovine)

UniProt ID  Q8WML4,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03743.cif

Structure  SPKB03743.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2399.95744

Aliphatic index  159.5454545

Isoelectric point  3.749987361

Charge (pH=7)   -1.001569216

Topological polar surface area  789.13

Aromaticity  0.090909091

Average rotatable bonds  3.227272727

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  29

X logP energy  -1.4952

Hydropathy 



Literature Information


Title  Purification of MUC1 from bovine milk-fat globules and characterization of a corresponding full-length cDNA clone.

DOI  10.3168/jds.S0022-0302(01)74713-3,

Publication Year  2001

PubMed ID  11814015,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.