SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03742

Signal sequence   MNKIYYLKYCHITKSLIAVSELARRVTCKSHRRLSRRVILTSVAALSLSSAWPALS

Length  56

Organism  Shigella flexneri

UniProt ID  Q8VSL2,

Motif  1..56



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03742.cif

Structure  SPKB03742.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6363.60134

Aliphatic index  115

Isoelectric point  11.22691301

Charge (pH=7)   9.053876926

Topological polar surface area  2587.5

Aromaticity  0.071428571

Average rotatable bonds  3.785714286

Number of hydrogen bond donors  100

Number of hydrogen bond acceptors  89

X logP energy  -24.11278

Hydropathy 



Literature Information


Title  SepA, the major extracellular protein of Shigella flexneri: autonomous secretion and involvement in tissue invasion.

DOI  10.1111/j.1365-2958.1995.mmi_17010123.x,

Publication Year  1995

PubMed ID  7476198,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.