SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03740

Signal sequence   MGLYPLIWLSLAACTAWG

Length  18

Organism  Mus musculus (Mouse)

UniProt ID  Q8VCT4,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03740.cif

Structure  SPKB03740.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1966.38624

Aliphatic index  125

Isoelectric point  5.919503212

Charge (pH=7)   -0.064840831

Topological polar surface area  641.5

Aromaticity  0.166666667

Average rotatable bonds  3.111111111

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  24

X logP energy  -0.8486

Hydropathy 



Literature Information


Title  Identification of di-(2-ethylhexyl) phthalate-induced carboxylesterase 1 in C57BL/6 mouse liver microsomes: purification, cDNA cloning, and baculovirus-mediated expression.

DOI  10.1124/dmd.104.000620,

Publication Year  2004

PubMed ID  15269189,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.