SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03739

Signal sequence   MKAWGALWIVLGLLLWPEPGAA

Length  22

Organism  Mus musculus (Mouse)

UniProt ID  Q8VCS0,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03739.cif

Structure  SPKB03739.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2392.93034

Aliphatic index  137.7272727

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  767.53

Aromaticity  0.136363636

Average rotatable bonds  3.181818182

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  1.4168

Hydropathy 



Literature Information


Title  A mammalian peptidoglycan recognition protein with N-acetylmuramoyl-L-alanine amidase activity.

DOI  10.1016/s0006-291x(03)01096-9,

Publication Year  2003

PubMed ID  12821140,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.