SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03733

Signal sequence   MRIAFFLLVLAVIIGFAYG

Length  19

Organism  Dictyostelium discoideum (Social amoeba)

UniProt ID  Q8T1G4,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03733.cif

Structure  SPKB03733.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2114.66294

Aliphatic index  169.4736842

Isoelectric point  9.348807885

Charge (pH=7)   0.997130574

Topological polar surface area  669.25

Aromaticity  0.210526316

Average rotatable bonds  3.473684211

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  1.72857

Hydropathy 



Literature Information


Title  A Dictyostelium mutant with reduced lysozyme levels compensates by increased phagocytic activity.

DOI  10.1074/jbc.M411445200,

Publication Year  2005

PubMed ID  15640146,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.