SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03732

Signal sequence   MKSTISLLLVVICTVVLAAQQSQA

Length  24

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  Q8SXL2,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03732.cif

Structure  SPKB03732.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2517.08084

Aliphatic index  158.3333333

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  989.06

Aromaticity  0

Average rotatable bonds  3.541666667

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  36

X logP energy  -9.1441

Hydropathy 



Literature Information


Title  Peptidomics and peptide hormone processing in the Drosophila midgut.

DOI  10.1021/pr101116g,

Publication Year  2011

PubMed ID  21214272,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.