SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03724

Signal sequence   MEQQNKRGLKRKALLGGVLGLGGLAMAG

Length  28

Organism  Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)

UniProt ID  Q8NNK2,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPII



Structure Information


PDB ID  7Q21,

Predicted Structure ID  SPKB03724.cif

Structure  SPKB03724.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2867.46714

Aliphatic index  104.6428571

Isoelectric point  11.75114598

Charge (pH=7)   3.998867698

Topological polar surface area  1217.45

Aromaticity  0

Average rotatable bonds  3.75

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  40

X logP energy  -12.40906

Hydropathy 



Literature Information


Title  Cytochrome c oxidase contains an extra charged amino acid cluster in a new type of respiratory chain in the amino-acid-producing Gram-positive bacterium Corynebacterium glutamicum.

DOI  10.1099/00221287-147-10-2865,

Publication Year  2001

PubMed ID  11577165,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.