General Information
SPKB ID SPKB03722
Signal sequence MVGQMYCYPGSHLARALTRALALALVLALLVGPFLSGLAGA
Length 41
Organism Homo sapiens (Human)
UniProt ID Q8NHP8,
Motif 1..41
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03722.cif
Physicochemical Information
Molecular weight 4187.09124
Aliphatic index 135.8536585
Isoelectric point 9.326158392
Charge (pH=7) 2.025211223
Topological polar surface area 1506.46
Aromaticity 0.073170732
Average rotatable bonds 3.195121951
Number of hydrogen bond donors 54
Number of hydrogen bond acceptors 54
X logP energy -9.75356
Hydropathy
Literature Information
Title Biochemical characterization and lysosomal localization of the mannose-6-phosphate protein p76 (hypothetical protein LOC196463).
DOI 10.1042/BJ20061205,
Publication Year 2007
PubMed ID 17105447,
Patent ID NA,