SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03721

Signal sequence   MGLHLRPYRVGLLPDGLLFLLLLLMLLADPALP

Length  33

Organism  Homo sapiens (Human)

UniProt ID  Q8NCC3,

Motif  1..33



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03721.cif

Structure  SPKB03721.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3655.59064

Aliphatic index  180.3030303

Isoelectric point  7.543574789

Charge (pH=7)   0.088929322

Topological polar surface area  1206.67

Aromaticity  0.060606061

Average rotatable bonds  3.454545455

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  42

X logP energy  0.31104

Hydropathy 



Literature Information


Title  Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.

DOI  10.1006/bbrc.1999.0411,

Publication Year  1999

PubMed ID  10092508,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.