SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03717

Signal sequence   MAAPALGLVCGRCPELGLVLLLLLLSLLCGAAG

Length  33

Organism  Homo sapiens (Human)

UniProt ID  Q8NBK3,

Motif  1..33



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03717.cif

Structure  SPKB03717.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3222.07034

Aliphatic index  174.5454545

Isoelectric point  6.068922519

Charge (pH=7)   -0.186168037

Topological polar surface area  1096.37

Aromaticity  0

Average rotatable bonds  3.121212121

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  41

X logP energy  -5.29113

Hydropathy 



Literature Information


Title  Molecular characterization of the human Calpha-formylglycine-generating enzyme.

DOI  10.1074/jbc.M413383200,

Publication Year  2005

PubMed ID  15657036,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.