Peptide-Information

General Information

SPKB ID SPKB03713

Signal sequence MAAEWASRFWLWATLLIPAAAV

Length 22

Organism Homo sapiens (Human)

UniProt ID Q8N766,

Motif 1..22

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID 6WW7,

Predicted Structure ID SPKB03713.cif

Structure SPKB03713.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2474.94884

Aliphatic index 115.9090909

Isoelectric point 6.410149741

Charge (pH=7) -0.000243889

Topological polar surface area 852.66

Aromaticity 0.181818182

Average rotatable bonds 3.227272727

Number of hydrogen bond donors 31

Number of hydrogen bond acceptors 28

X logP energy -1.26603

Hydropathy

Literature Information

Title Structural basis for membrane insertion by the human ER membrane protein complex.

Publication Year 2020

PubMed ID 32439656,

Patent ID NA,