SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03712

Signal sequence   MSAVLLLALLGFILPLPGVQA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  Q8N6Q3,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03712.cif

Structure  SPKB03712.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2136.70734

Aliphatic index  190.4761905

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  691.06

Aromaticity  0.047619048

Average rotatable bonds  3.142857143

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  25

X logP energy  -0.6364

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.