SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03706

Signal sequence   MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDS

Length  41

Organism  Homo sapiens (Human)

UniProt ID  Q8N0W4,

Motif  1..41



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03706.cif

Structure  SPKB03706.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4629.68684

Aliphatic index  149.7560976

Isoelectric point  8.545113874

Charge (pH=7)   0.936157722

Topological polar surface area  1608.4

Aromaticity  0.097560976

Average rotatable bonds  3.536585366

Number of hydrogen bond donors  56

Number of hydrogen bond acceptors  57

X logP energy  -6.08063

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.