General Information
SPKB ID SPKB03704
Signal sequence MFRKFVIMLVLSLLVAAGISQA
Length 22
Organism Tyria jacobaeae (Cinnabar moth)
UniProt ID Q8MP06,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03704.cif
Physicochemical Information
Molecular weight 2408.04484
Aliphatic index 159.5454545
Isoelectric point 11.65177567
Charge (pH=7) 1.997685954
Topological polar surface area 845.89
Aromaticity 0.090909091
Average rotatable bonds 3.681818182
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 30
X logP energy -2.85123
Hydropathy
Literature Information
Title Evolutionary recruitment of a flavin-dependent monooxygenase for the detoxification of host plant-acquired pyrrolizidine alkaloids in the alkaloid-defended arctiid moth Tyria jacobaeae.
Publication Year 2002
PubMed ID 11972041,
Patent ID NA,