SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03701

Signal sequence   MRFQLFYILGLLSVTSLTHA

Length  20

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  Q8MM24,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03701.cif

Structure  SPKB03701.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2310.78264

Aliphatic index  136.5

Isoelectric point  9.351184298

Charge (pH=7)   1.088039665

Topological polar surface area  851.04

Aromaticity  0.15

Average rotatable bonds  3.7

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -4.37903

Hydropathy 



Literature Information


Title  A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells.

DOI  10.1242/dev.126.2.211,

Publication Year  1999

PubMed ID  9847235,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.