SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03700

Signal sequence   MTGSLWLSLALSLAVLAQFKVSA

Length  23

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  Q8MLZ7,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03700.cif

Structure  SPKB03700.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2406.90904

Aliphatic index  144.3478261

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  889.57

Aromaticity  0.086956522

Average rotatable bonds  3.391304348

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  32

X logP energy  -6.1722

Hydropathy 



Literature Information


Title  A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells.

DOI  10.1242/dev.126.2.211,

Publication Year  1999

PubMed ID  9847235,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.