SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03696

Signal sequence   MTSRYRSSEAHQGLASFSPRRRTVVKAAAATAVLAGPLAAALPARA

Length  46

Organism  Streptomyces chromofuscus

UniProt ID  Q8KRU5,

Motif  1..46



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03696.cif

Structure  SPKB03696.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4737.46684

Aliphatic index  81.08695652

Isoelectric point  12.50674501

Charge (pH=7)   6.089503197

Topological polar surface area  2035.01

Aromaticity  0.043478261

Average rotatable bonds  3.260869565

Number of hydrogen bond donors  75

Number of hydrogen bond acceptors  67

X logP energy  -25.74048

Hydropathy 



Literature Information


Title  A 20-kDa domain is required for phosphatidic acid-induced allosteric activation of phospholipase D from Streptomyces chromofuscus.

DOI  10.1016/s0167-4838(99)00005-9,

Publication Year  1999

PubMed ID  10082951,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.