SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03687

Signal sequence   MKFSSIILLTLLICSMSKFGNC

Length  22

Organism  Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)

UniProt ID  Q8I0L5,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03687.cif

Structure  SPKB03687.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2450.06884

Aliphatic index  124.0909091

Isoelectric point  8.821677593

Charge (pH=7)   1.8734448

Topological polar surface area  870.7

Aromaticity  0.090909091

Average rotatable bonds  3.818181818

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  35

X logP energy  -6.1322

Hydropathy 



Literature Information


Title  A new class of scorpion toxin binding sites related to an A-type K+ channel: pharmacological characterization and localization in rat brain.

DOI  10.1016/s0014-5793(01)02620-5,

Publication Year  2001

PubMed ID  11457451,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.