SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03686

Signal sequence   MSGMWVHPGRTLIWALWVLAAVIKGPAA

Length  28

Organism  Felis catus (Cat) (Felis silvestris catus)

UniProt ID  Q8I034,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03686.cif

Structure  SPKB03686.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3032.70394

Aliphatic index  118.5714286

Isoelectric point  11.65178972

Charge (pH=7)   2.088595045

Topological polar surface area  1035.87

Aromaticity  0.107142857

Average rotatable bonds  3.214285714

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  36

X logP energy  -2.89813

Hydropathy 



Literature Information


Title  Molecular cloning and characterization of a novel carboxylesterase-like protein that is physiologically present at high concentrations in the urine of domestic cats (Felis catus).

DOI  10.1042/BJ20021446,

Publication Year  2003

PubMed ID  12401131,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.