SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03684

Signal sequence   MNCSAFSFWFVCKIIFFFLSFHIQISIA

Length  28

Organism  Cannabis sativa (Hemp) (Marijuana)

UniProt ID  Q8GTB6,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03684.cif

Structure  SPKB03684.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3348.04394

Aliphatic index  101.0714286

Isoelectric point  8.241247528

Charge (pH=7)   0.964648925

Topological polar surface area  1086.61

Aromaticity  0.285714286

Average rotatable bonds  3.714285714

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  40

X logP energy  -2.2992

Hydropathy 



Literature Information


Title  The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L.

DOI  10.1074/jbc.M403693200,

Publication Year  2004

PubMed ID  15190053,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.