SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03683

Signal sequence   MKLSFSLCIFFFNLLLLLQAVIS

Length  23

Organism  Platanus acerifolia (London plane tree)

UniProt ID  Q8GT41,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03683.cif

Structure  SPKB03683.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2661.34224

Aliphatic index  169.5652174

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  876.41

Aromaticity  0.173913043

Average rotatable bonds  3.826086957

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -0.9448

Hydropathy 



Literature Information


Title  Purification and characterization of Pla a 1, a major allergen from Platanus acerifolia pollen.

DOI  10.1034/j.1398-9995.2002.03406.x,

Publication Year  2002

PubMed ID  11906336,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.