SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03675

Signal sequence   MRRGFGPLSLAFFLFLLALLTLPGDG

Length  26

Organism  Mus musculus (Mouse)

UniProt ID  Q8BSU2,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03675.cif

Structure  SPKB03675.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2823.43494

Aliphatic index  127.6923077

Isoelectric point  10.39776887

Charge (pH=7)   0.998424161

Topological polar surface area  974.8

Aromaticity  0.153846154

Average rotatable bonds  3.384615385

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -3.43686

Hydropathy 



Literature Information


Title  A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.

DOI  10.1038/79738,

Publication Year  2000

PubMed ID  11017100,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.