SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03674

Signal sequence   MAYSTVQRVALASGLVLAVSLLLPKAFLSRG

Length  31

Organism  Mus musculus (Mouse)

UniProt ID  Q8BPM6,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03674.cif

Structure  SPKB03674.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3232.91884

Aliphatic index  141.6129032

Isoelectric point  11.53052052

Charge (pH=7)   2.996832229

Topological polar surface area  1241.82

Aromaticity  0.064516129

Average rotatable bonds  3.387096774

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  43

X logP energy  -10.02736

Hydropathy 



Literature Information


Title  Mouse RIC-3, an endoplasmic reticulum chaperone, promotes assembly of the alpha7 acetylcholine receptor through a cytoplasmic coiled-coil domain.

DOI  10.1523/JNEUROSCI.1776-09.2009,

Publication Year  2009

PubMed ID  19812337,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.