SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03673

Signal sequence   MPLYKLLGWLNAVACGVLLLVLHVQG

Length  26

Organism  Mus musculus (Mouse)

UniProt ID  Q8BK48,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03673.cif

Structure  SPKB03673.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2821.52114

Aliphatic index  172.3076923

Isoelectric point  8.530526343

Charge (pH=7)   1.025773226

Topological polar surface area  958.93

Aromaticity  0.076923077

Average rotatable bonds  3.423076923

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -1.4578

Hydropathy 



Literature Information


Title  Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes.

DOI  10.1074/jbc.M403673200,

Publication Year  2004

PubMed ID  15123619,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.