SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03669

Signal sequence   MWKVSALLFVLGSASLWVLAEG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  Q86YL7,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03669.cif

Structure  SPKB03669.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2377.87004

Aliphatic index  141.8181818

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  830.01

Aromaticity  0.136363636

Average rotatable bonds  3.409090909

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -2.4854

Hydropathy 



Literature Information


Title  Functional glycosylation of human podoplanin: glycan structure of platelet aggregation-inducing factor.

DOI  10.1016/j.febslet.2006.12.044,

Publication Year  2007

PubMed ID  17222411,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.