SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03665

Signal sequence   MVAVLGGRGVLRLRLLLSALKPGIHVPRAGPAAAFGT

Length  37

Organism  Homo sapiens (Human)

UniProt ID  Q86WA6,

Motif  1..37



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03665.cif

Structure  SPKB03665.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3736.57284

Aliphatic index  131.8918919

Isoelectric point  12.98094644

Charge (pH=7)   5.088585111

Topological polar surface area  1427.31

Aromaticity  0.027027027

Average rotatable bonds  3.216216216

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  47

X logP energy  -11.21292

Hydropathy 



Literature Information


Title  Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase.

DOI  10.1074/jbc.M302055200,

Publication Year  2003

PubMed ID  12732646,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.