SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03663

Signal sequence   MKVLILIMIIASLMIMGVEM

Length  20

Organism  Centruroides noxius (Mexican scorpion)

UniProt ID  Q86QT3,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03663.cif

Structure  SPKB03663.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2250.01714

Aliphatic index  190

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  699.77

Aromaticity  0

Average rotatable bonds  4

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  29

X logP energy  1.6932

Hydropathy 



Literature Information


Title  A toxin to nervous, cardiac, and endocrine ERG K+ channels isolated from Centruroides noxius scorpion venom.

DOI  NA,

Publication Year  1999

PubMed ID  10224238,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.