SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03661

Signal sequence   MKAIFVSALLVVALVASTSA

Length  20

Organism  Rhipicephalus microplus (Cattle tick) (Boophilus microplus)

UniProt ID  Q86LE5,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03661.cif

Structure  SPKB03661.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1991.46024

Aliphatic index  161

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  723.16

Aromaticity  0.05

Average rotatable bonds  3.2

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -5.0001

Hydropathy 



Literature Information


Title  Cysteine-rich antimicrobial peptides of the cattle tick Boophilus microplus: isolation, structural characterization and tissue expression profile.

DOI  10.1016/j.dci.2003.08.001,

Publication Year  2004

PubMed ID  14642886,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.