SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03659

Signal sequence   MDLSRRLCSTALVAFIVLASIHDSQS

Length  26

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  Q868Z9,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03659.cif

Structure  SPKB03659.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2834.30134

Aliphatic index  123.8461538

Isoelectric point  7.360361381

Charge (pH=7)   0.02780502

Topological polar surface area  1182.37

Aromaticity  0.038461538

Average rotatable bonds  3.615384615

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  41

X logP energy  -12.85826

Hydropathy 



Literature Information


Title  Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases.

DOI  10.1242/dev.127.24.5475,

Publication Year  2000

PubMed ID  11076767,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.