SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03657

Signal sequence   MAKCSYVFCAVLLIFIVAIGEMEA

Length  24

Organism  Artemisia vulgaris (Mugwort)

UniProt ID  Q84ZX5,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03657.cif

Structure  SPKB03657.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2622.25244

Aliphatic index  134.1666667

Isoelectric point  4.258067521

Charge (pH=7)   -1.123560335

Topological polar surface area  873.7

Aromaticity  0.125

Average rotatable bonds  3.541666667

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -1.8914

Hydropathy 



Literature Information


Title  Art v 1, the major allergen of mugwort pollen, is a modular glycoprotein with a defensin-like and a hydroxyproline-rich domain.

DOI  10.1096/fj.02-0472fje,

Publication Year  2003

PubMed ID  12475905,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.