SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03654

Signal sequence   METTTKLAIGVSALCCLASAAFA

Length  23

Organism  Coxiella burnetii (strain RSA 493 / Nine Mile phase I)

UniProt ID  Q83EK8,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03654.cif

Structure  SPKB03654.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2272.71824

Aliphatic index  106.5217391

Isoelectric point  6.13535235

Charge (pH=7)   -0.124485044

Topological polar surface area  867.99

Aromaticity  0.043478261

Average rotatable bonds  3.173913043

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -9.3687

Hydropathy 



Literature Information


Title  Cloning and porin activity of the major outer membrane protein P1 from Coxiella burnetii.

DOI  10.1128/IAI.70.12.6741-6750.2002,

Publication Year  2002

PubMed ID  12438349,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.