SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03653

Signal sequence   MRQILVLLLFATLVYG

Length  16

Organism  Xenopus laevis (African clawed frog)

UniProt ID  Q805F3,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03653.cif

Structure  SPKB03653.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1850.33604

Aliphatic index  188.75

Isoelectric point  9.348807885

Charge (pH=7)   0.997130574

Topological polar surface area  645.27

Aromaticity  0.125

Average rotatable bonds  3.75

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  -0.23613

Hydropathy 



Literature Information


Title  Differential expression of two cathepsin Es during metamorphosis-associated remodeling of the larval to adult type epithelium in Xenopus stomach.

DOI  10.1093/jb/mvg156,

Publication Year  2003

PubMed ID  14561724,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.