SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03648

Signal sequence   MTRWVQTFLLLVAVIRSYA

Length  19

Organism  Xenopus laevis (African clawed frog)

UniProt ID  Q7ZT75,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03648.cif

Structure  SPKB03648.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2267.76074

Aliphatic index  138.4210526

Isoelectric point  11.14762293

Charge (pH=7)   1.997127263

Topological polar surface area  850.72

Aromaticity  0.157894737

Average rotatable bonds  3.736842105

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  28

X logP energy  -3.46906

Hydropathy 



Literature Information


Title  Molecular cloning and characterization of novel ficolins from Xenopus laevis.

DOI  10.1007/s00251-003-0552-2,

Publication Year  2003

PubMed ID  12679857,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.