SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03645

Signal sequence   MKYLFIAIILILYCSFTKA

Length  19

Organism  Dictyostelium discoideum (Social amoeba)

UniProt ID  Q7YSJ4,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03645.cif

Structure  SPKB03645.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2251.85674

Aliphatic index  154.2105263

Isoelectric point  9.274958252

Charge (pH=7)   1.933718687

Topological polar surface area  720.08

Aromaticity  0.210526316

Average rotatable bonds  3.842105263

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  1.1832

Hydropathy 



Literature Information


Title  A cysteine-rich extracellular protein containing a PA14 domain mediates quorum sensing in Dictyostelium discoideum.

DOI  10.1128/EC.4.6.991-998.2005,

Publication Year  2005

PubMed ID  15947191,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.