SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03644

Signal sequence   MCAPGYHRFWFHWGLLLLLLLEAPLRGLA

Length  29

Organism  Mus musculus (Mouse)

UniProt ID  Q7TQN3,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03644.cif

Structure  SPKB03644.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3395.13504

Aliphatic index  131.3793103

Isoelectric point  8.542060462

Charge (pH=7)   1.118745851

Topological polar surface area  1130.81

Aromaticity  0.172413793

Average rotatable bonds  3.517241379

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  38

X logP energy  0.24144

Hydropathy 



Literature Information


Title  Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains.

DOI  10.1210/me.2002-0366,

Publication Year  2003

PubMed ID  12595574,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.