SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03643

Signal sequence   MTRMLDLGLFLAGLLTVKGL

Length  20

Organism  Mus musculus (Mouse)

UniProt ID  Q7TMF5,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03643.cif

Structure  SPKB03643.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2162.72034

Aliphatic index  156

Isoelectric point  9.695024739

Charge (pH=7)   0.998132438

Topological polar surface area  781.9

Aromaticity  0.05

Average rotatable bonds  3.7

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -3.12023

Hydropathy 



Literature Information


Title  Visceral adipose tissue-derived serine protease inhibitor: a unique insulin-sensitizing adipocytokine in obesity.

DOI  10.1073/pnas.0504703102,

Publication Year  2005

PubMed ID  16030142,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.