SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03640

Signal sequence   MPPLFQALTTALFFCGIASNPL

Length  22

Organism  Xenopus laevis (African clawed frog)

UniProt ID  Q7SZI7,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03640.cif

Structure  SPKB03640.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2352.83474

Aliphatic index  102.2727273

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  794.92

Aromaticity  0.136363636

Average rotatable bonds  3.090909091

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  30

X logP energy  -4.6749

Hydropathy 



Literature Information


Title  Purification of the full-length Xenopus interphotoreceptor retinoid binding protein and growth of diffraction-quality crystals.

DOI  NA,

Publication Year  2007

PubMed ID  18079675,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.