SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03638

Signal sequence   MKLGCVLMAWALYLSLGVLWVAQMLLA

Length  27

Organism  Homo sapiens (Human)

UniProt ID  Q7L513,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03638.cif

Structure  SPKB03638.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2994.80924

Aliphatic index  162.5925926

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  961.07

Aromaticity  0.111111111

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  36

X logP energy  0.6545

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.