SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03635

Signal sequence   MNQIHKFFCNMTQCSQGGAGELPTVKEKTCKLSFSPFVVGASLLLGGPIAFA

Length  52

Organism  Shigella flexneri

UniProt ID  Q7BCK4,

Motif  1..52



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03635.cif

Structure  SPKB03635.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5505.48644

Aliphatic index  76.92307692

Isoelectric point  8.520022905

Charge (pH=7)   1.905339353

Topological polar surface area  2085.47

Aromaticity  0.096153846

Average rotatable bonds  3.461538462

Number of hydrogen bond donors  72

Number of hydrogen bond acceptors  77

X logP energy  -20.8202

Hydropathy 



Literature Information


Title  Unipolar localization and ATPase activity of IcsA, a Shigella flexneri protein involved in intracellular movement.

DOI  10.1128/jb.175.8.2189-2196.1993,

Publication Year  1993

PubMed ID  8468279,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.