SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03633

Signal sequence   MPLKRNTGLMILMLCTLALWAKSVSA

Length  26

Organism  Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

UniProt ID  Q76IQ4,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03633.cif

Structure  SPKB03633.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2862.60454

Aliphatic index  127.6923077

Isoelectric point  10.79319833

Charge (pH=7)   2.935416204

Topological polar surface area  1035.77

Aromaticity  0.038461538

Average rotatable bonds  3.653846154

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  39

X logP energy  -6.24973

Hydropathy 



Literature Information


Title  Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout.

DOI  10.1210/en.2003-1085,

Publication Year  2003

PubMed ID  12970156,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.