SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03617

Signal sequence   MGTPRAQHPPPPQLLFLILLSCPWIQG

Length  27

Organism  Homo sapiens (Human)

UniProt ID  Q6UXD5,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03617.cif

Structure  SPKB03617.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3011.63904

Aliphatic index  104.8148148

Isoelectric point  8.557478416

Charge (pH=7)   1.026915363

Topological polar surface area  1043.28

Aromaticity  0.074074074

Average rotatable bonds  3.185185185

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  37

X logP energy  -5.30603

Hydropathy 



Literature Information


Title  Enrichment of glycopeptides for glycan structure and attachment site identification.

DOI  10.1038/nmeth.1392,

Publication Year  2009

PubMed ID  19838169,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.